Variability of μ-Calpain and Calpastatin genes in cattle
نویسندگان
چکیده
منابع مشابه
Genetic Variability of Calpastatin and Calpain Genes in Iranian Zel Sheep Using PCR-RFLP and PCR-SSCP Methods
The genotypes for calpastatin (CAST) and calpain (CAPN) loci were determined by PCR-RFLP and PCRSSCPmethods. Blood samples were collected from 200 pure-bred Zel sheep from Shirang’s Zel sheep Breeding Station located in south-west of Golestan, Iran. Extraction of genomic DNA was performed based on the modified salting out method. Based on results, two investigated loci were polymorphic an...
متن کاملEffects of polymorphisms in the calpastatin and μ-calpain genes on meat tenderness in 3 French beef breeds.
The objectives of the study were to evaluate allelic frequencies and to test the association of polymorphisms in the calpastatin (CAST) and µ-calpain (CAPN1) genes with meat tenderness in 3 French beef breeds. A total of 1,114 Charolais, 1,254 Limousin, and 981 Blonde d'Aquitaine purebred young bulls were genotyped for 3 SNP in the CAST gene and 4 SNP in the CAPN1 gene. Two of these markers, 1 ...
متن کاملAssociation of μ-Calpain and Calpastatin Polymorphisms with Meat Tenderness in a Brahman–Angus Population
Autogenous proteolytic enzymes of the calpain family are implicated in myofibrillar protein degradation. As a result, the μ-calpain gene and its specific inhibitor, calpastatin, have been repeatedly investigated for their association with meat quality traits in cattle; however, no functional mutation has been identified for these two genes. The objectives of this study were: (1) to assess breed...
متن کاملEffects of calpastatin and -calpain markers in beef cattle on tenderness traits1,2
The objective of this study was to assess the association of single nucleotide polymorphisms (SNP) developed at the calpastatin (CAST) and -calpain (CAPN1) genes with meat tenderness and palatability traits in populations with diverse genetic backgrounds. Three populations were used in the study. One population consisted of Bos taurus that included crossbred animals derived from Hereford, Angus...
متن کاملEpistasis between calpain 1 and its inhibitor calpastatin within breeds of cattle.
The calpain gene family and its inhibitors have diverse effects, many related to protein turnover, which appear to affect a range of phenotypes such as diabetes, exercise-induced muscle injury, and pathological events associated with degenerative neural diseases in humans, fertility, longevity, and postmortem effects on meat tenderness in livestock species. The calpains are inhibited by calpast...
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ژورنال
عنوان ژورنال: Italian Journal of Animal Science
سال: 2009
ISSN: 1828-051X
DOI: 10.4081/ijas.2009.s2.99